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Bioinformatics

Statistical Genomics: Methods and Protocols

This volume expands on statistical analysis of genomic data by discussing cross-cutting groundwork material, public data repositories, common applications, and representative tools for operating on genomic data. Statistical Genomics: Methods and Protocols is divided into four sections. The first section discusses overview materi...

Data Mining Techniques for the Life Sciences (2nd Edition)

This volume details several important databases and data mining tools. Data Mining Techniques for the Life Sciences, Second Edition guides readers through archives of macromolecular three-dimensional structures, databases of protein-protein interactions, thermodynamics information on protein and mutant stability, “Kbdock” protei...

Synthetic mRNA: Production, Introduction Into Cells, and Physiological Consequences

This volume presents detailed laboratory protocols for in vitro synthesis of mRNA with favorable properties, its introduction into cells by a variety of techniques, and the measurement of physiological and clinical consequences such as protein replacement and cancer immunotherapy. Synthetic techniques are described for structura...

Forensic DNA Typing Protocols (2nd Edition)

This volume presents a series of protocols and methods, some of which are not widely used by researchers/practitioners, and will aid in the execution of different laboratory techniques. Forensic DNA Typing Protocols, Second Edition is arranged into a series of related chapters. Chapter 1-3 examines two different aspects of RNA a...

Digital PCR: Methods and Protocols

This volume explores and explains how digital PCRs (dPCRs) help in the study of numerous topics, such as infectious diseases, evolution of cancer and treatment responses, somatic mosaicism, genome editing and cell therapy, and food testing for GMOs and pathogens. Written in the highly successful Methods in Molecular Biology seri...

Basic applied bioinformatics

An accessible guide that introduces students in all areas of life sciences to bioinformatics. Basic Applied Bioinformatics provides a practical guidance in bioinformatics and helps students to optimize parameters for data analysis and then to draw accurate conclusions from the results.

Scalable Big Data Analytics for Protein Bioinformatics: Efficient Computational Solutions for Protein Structures

This book presents a focus on proteins and their structures. The text describes various scalable solutions for protein structure similarity searching, carried out at main representation levels and for prediction of 3D structures of proteins. Emphasis is placed on techniques that can be used to accelerate similarity searches and ...

Bioinformatics Algorithms: Design and Implementation in Python (1st Edition)

Bioinformatics Algorithms: Design and Implementation in Python provides a comprehensive book on many of the most important bioinformatics problems, putting forward the best algorithms and showing how to implement them. The book focuses on the use of the Python programming language and its algorithms, which is quickly becoming th...

Molecular Feminisms: Biology, Becomings, and Life in the Lab

"Should feminists clone?" "What do neurons think about?" "How can we learn from bacterial writing?" These and other provocative questions have long preoccupied neuroscientist, molecular biologist, and intrepid feminist theorist Deboleena Roy, who takes seriously the capabilities of lab "objects" - bacteria and other human, nonhu...